| Title |
Inhaled Vasoactive Intestinal Peptide Exerts Immunoregulatory Effects in Sarcoidosis
|
|---|---|
| Published in |
American Journal of Respiratory & Critical Care Medicine, May 2010
|
| DOI | 10.1164/rccm.200909-1451oc |
| Pubmed ID | |
| Authors |
Antje Prasse, Gernot Zissel, Niklas Lützen, Jonas Schupp, Rene Schmiedlin, Elena Gonzalez-Rey, Anne Rensing-Ehl, Gerald Bacher, Vera Cavalli, Dorian Bevec, Mario Delgado, Joachim Müller-Quernheim |
| Abstract |
Previous studies suggest an important immunoregulatory role of vasoactive intestinal peptide (VIP) in experimental models of chronic noninfectious inflammation. Sarcoidosis is characterized by noncaseating epitheloid cell granulomas, where excessive tumor necrosis factor-alpha production by pulmonary macrophages plays a critical role in granuloma formation and disease progression, which may lead to fatal organ dysfunction. |
Mendeley readers
The data shown below were compiled from readership statistics for 54 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 54 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 9 | 17% |
| Student > Ph. D. Student | 8 | 15% |
| Student > Bachelor | 6 | 11% |
| Other | 5 | 9% |
| Student > Postgraduate | 3 | 6% |
| Other | 9 | 17% |
| Unknown | 14 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 17 | 31% |
| Agricultural and Biological Sciences | 10 | 19% |
| Immunology and Microbiology | 5 | 9% |
| Biochemistry, Genetics and Molecular Biology | 4 | 7% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 2% |
| Other | 2 | 4% |
| Unknown | 15 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 20. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 October 2023.
All research outputs
#1,891,602
of 25,374,647 outputs
Outputs from American Journal of Respiratory & Critical Care Medicine
#1,593
of 12,493 outputs
Outputs of similar age
#6,537
of 104,303 outputs
Outputs of similar age from American Journal of Respiratory & Critical Care Medicine
#10
of 67 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 12,493 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.9. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 104,303 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 67 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 85% of its contemporaries.